The Master Quilter opens with the sound of wedding bells ringing in the ears of the Elm Creek Quilters. The close-knit group can hardly believe that their own Sylvia Compson planned her holiday wedding to sweetheart Andrew in complete secrecy, without the help of even one of her friends. Eager to honour the newlyweds, the Elm Creek Quilters hasten to stitch a bridal quilt for their favourite Master Quilter.

As the quilt blocks accumulate, the Elm Creek Quilters celebrate the joy of new beginnings and the ongoing success of their business - until forces conspire to threaten their happiness and prosperity. Two among them falter in their personal relationships, yet they are too proud to share their pain. The financial problems of another leave the quilt project vulnerable to a malicious act that may prevent its completion. And as two others weigh the comfort of the present against dreams of a future far from Elm Creek Manor, closely guarded secrets strain the bonds of friendship with those who may be left behind.